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Deschloroetizolam is a short-acting psychoactive substance of the thienodiazepine class which has been shown to produce depressant, anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant and amnesic effects. Deschloroetizolam, like benzodiazepines, binds to modulatory sites on the GABA receptors. Deschloroetizolam is closely related to etizolam (Etilaam), triazolam (Halcion), and alprazolam (Xanax).[2] It is not prescribed and is not recognised as a controlled substance in many parts of the world, leading to its appearance within grey market research chemical vendors in 2014.

Deschloroetizolam has a relatively fast onset of action and symptomatic relief. It is half as potent as its parent compound etizolam with a duration which is twice as long. It also has a similar bioavailibility and a similar time to onset in comparison to the parent drug. 2mg of deschloroetizolam is thought to be of similar potency to 10mg of diazepam.

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Thirdly, Deschloroetizolam contains a thiophene ring fused to a diazepine ring. Which is a seven member ring with the two nitrogen constituents located at R1 and R4. Thiophene is a five member aromatic ring with one sulfur atom. This forms the thienodiazepine core of deschloroetizolam. Additionally, a phenyl ring is bound to this structure at R5. Deschloroetizolam also contains a methylated triazole ring fused to and incorporating R1 and R2 of its diazepine ring. Deschloroetizolam shares this fused triazole ring substitution with certain benzodiazepine drugs, called triazolobenzodiazepines, distinguished by the suffix “-zolam.

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Thienodiazepines produce a variety of effects by binding to the benzodiazepine receptor site and magnifying the efficiency. And effects of the neurotransmitter gamma aminobutyric acid (GABA) by acting on its receptors.  As this site is the most prolific inhibitory receptor set within the brain, its modulation results in the sedating (or calming effects) of deschloroetizolam on the nervous system.https://www.pureresearchchemical.com/product/deschloroetizolam-powder-for-sale/

Sedation – In terms of energy level alterations, this drug has the potential to be extremely sedating and often results in an overwhelmingly lethargic state. At higher levels, this causes users to suddenly feel as if they are extremely sleep deprive and have not slept for days. Forcing them to sit down and generally feel as if they are constantly on the verge of passing out instead of engaging in physical activities. This sense of sleep deprivation increases proportional to dosage and eventually. Becomes powerful enough to force a person into complete unconsciousness.

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