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5F-ADB Powder for sale
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    5F-ADB Powder for sale

    Rated 5.00 out of 5 based on 6 customer ratings
    (6 customer reviews)

    $500.00 – $13,000.00

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    Description

    Buy 5F-ADB Powder

    What is 5F-ADB Powder?

    Firstly, 5F-ADB (also known as 5F-MDMB-PINACA) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family. 5F-MDMB-PINACA is widely use as an active ingredient in synthetic cannabis products.5F-ADB Powder for sale

    Secondly, Buy 5F-ADB is a potent agonist of the CB1 receptor, though it is unclear whether it is selective for this target. 5F-ADB is believe to be extremely potent based on the very low levels detected in tissue samples.

    Cas No: 1715016-75-3
    Formula: C20H28FN3O3
    IUPAC: Name: Methyl (S)-2-[1-(5-fluoropentyl)-1H-indazole-3-carboxamido]-3,3-dimethylbutanoate.

    Order 5F-ADB Powder

    Solubility: 5F-ADB is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dimethyl formamide. The solubility of 5F-ADB in these solvents is approximately 25 mg/ml. 5F-ADB is sparingly soluble in aqueous buffers. 7
    F. Identification and Analysis Quantification of 5F-ADB in products can be carry out according to the general
    procedure described by United Nations Office on Drugs and Crime (UNODC). 8

    Thirdly, The analytical profile of 5F-ADB has been describe in various papers. In this paragraph, Utilize methods include gas chromatography–mass spectrometry (GC-MS)1, 4, 9, 10 , liquid chromatography–tandem mass spectrometry (LC-MS/MS) 10, Fourier-transform infrared spectroscopy (FTIR)6, 9 and nuclear magnetic resonance spectroscopy,(NMR)6, 10. Moreover, Detection of 5F-ADB in biological matrices was describe in postmortem blood 3and tissue. In this paragraph, In urine samples, the main metabolites are the analytical targets.

    Purchase 5F-ADB Powder

    In this paragraph, Ease of Convertibility Into Controlled Substances 5F-ADB is not readily converted into other internationally controlled substances. 4. General Pharmacology 5F-ADB is a synthetic cannabinoid receptor agonist (SCRA).

    Moreover, It has an indazole core, which is a common structural feature in a number of the SCRAs monitore by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) and the UNODC.
    Finally, A. Routes of administration and dosage 5F-ADB is mainly offered on the Internet either in the form of ‘herbal mixtures’, where the chemical has been sprayed on plant material, as a powder, or in a liquid to be used in e-cigarette devices. Moreover, The effects of 5F-ADB are felt on doses as small as 50 micrograms on cigarettes or buds. To conclude,  Users reported strong cannabimimetic effects after smoking the drug. 5F-ADB Powder for sale

    Additional information
    Quantity

    25 Grams, 50 Grams, 100 Grams, 250 Grams, 500 Grams, 1 Kilogram

    Reviews (6)

    6 reviews for 5F-ADB Powder for sale

    1. Rated 5 out of 5

      David D – September 1, 2022

      Good customer service

    2. Rated 5 out of 5

      Milan – September 23, 2022

      Products are fine quality!

    3. Rated 5 out of 5

      Daan – October 3, 2022

      Reliable and honest

    4. Rated 5 out of 5

      Simo – October 19, 2022

      Good customer service

    5. Rated 5 out of 5

      Franck M – November 1, 2022

      Fast and great customer service

    6. Rated 5 out of 5

      Rainer Barzel – December 6, 2022

      I am so happy with Pure Research Chemical. Parcel of 2kg was delivered to me in Germany safely and product quality was excellent. I will come back again

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    PHP is commonly referred to as alpha-pyrrolidinyl-hexaphenone, PHP, and alpha-PHP. The IUPAC name for a-PHP is (±)-1-Phenyl-2-(1-pyrrolidinyl)-1-hexanone. We can look at the research conducted on this research chemical.
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    The family of phenylpiperidines (characterized by a phenyl moiety directly linked to a piperidine) includes also the NSO fentanyl (synthesized by P. Janssen in the 1960s) and its analogs, up to 1000 times more potent as analgesic than meperidine and differing in structure from the latter for a phenethyl group on the piperidine nitrogen in place of a methyl group (Elbaridi et al., 2017; Raffa et al., 2018).While extensive literature has been published in regards to pharmacology and toxicology of fentanyl and its illicit analogs (Bäckberg et al., 2015; Mounteney et al., 2015; Dwyer et al., 2017; Giorgetti et al., 2017; Guerrieri et al., 2017; Helander et al., 2017a; Pichini et al., 2017a,b; Shoff et al., 2017; Suzuki and El-Haddad, 2017), the pharmacological and toxicological properties of non-fentanyl derived NSOs have not yet been reviewed in detail.Compounds such as U-47700, U-51754, U-49900, U-448800, AH-7921 from the chemical family of benzamide, U-50488 and U-51754 from the acetamide family and MT-45 from the piperazine family are the NSOs most recently reported as health threats for opioids consumers (Mohr et al., 2016; Amin et al., 2017; Baumann et al., 2017; Domanski et al., 2017; Fabregat-Safont et al., 2017; Prekupec et al., 2017; Marchei et al., 2018). Indeed, this new generation of derivatives has been involved in a number of recent overdose deaths worldwide (Drug Enforcement Administration [DEA], 2016; Baumann et al., 2017; Domanski et al., 2017; Fabregat-Safont et al., 2017).Clandestine manufacturing of NSOs has been pirated from scientific literature or patent filings published by pharmaceutical companies attempting to search for new therapeutic drugs without addiction-related adverse effects (Logan et al., 2017).In a similar manner to fentanyl derivatives, these NSOs are being partly used as heroin adulterants or as constituents of counterfeit pain pills and they can be bought directly by users from online vendors via conventional web or cryptomarket (European Monitoring Centre for Drugs, and Drug Addiction [EMCDDA], 2016; Armenian et al., 2017b; Baumann et al., 2017; Van Hout and Hearne, 2017).Similarly to morphine and heroin (opiates) or to semi-synthetic opioids (like hydro- and oxycodone, hydro- and oxymorphone), these compounds produce CNS depressants effects such as respiratory depression, analgesia, hypothermia, sedation, euphoria, anxiety, sweating, disorientation, drowsiness, nausea, and miosis (Carroll et al., 2012; Guerrini et al., 2013; Hill and Thomas, 2016; Armenian et al., 2017b), and although the effects of tolerance and dependence may rapidly reach high levels, elevated risks of overdose and death are frequent for these compounds (United Nations Office on Drugs and Crime [UNODC], 2017b). Furthermore, the typical rewarding characteristics and the easy availability induce users to abuse of these opioids (Carroll et al., 2012).The main NSOs AH-7921, MT-45, and U-47700 have been identified in Europe between 2013 and 2016, and over 40 deaths were reported to the European Monitoring Centre for Drugs and Drug Addiction in a short time after that AH-7921 and MT-45 were found out on the European drug market (EMCDDA) (European Monitoring Centre for Drugs, and Drug Addiction [EMCDDA], 2017). Moreover, in 2016 U-47700 has been the cause of at least 46 confirmed fatalities as well as the subject of 88 reports from forensic laboratories submissions in the United States (Fabregat-Safont et al., 2017).Since the popularity of these substances is rapidly increasing and evolving over time, there is a great need to update all possible information, particularly with respect to their subjective and side effects and to tackle unsolved issues, including limited analytical methods to disclose and monitor different compounds (Katselou et al., 2015; Lucyk and Nelson, 2017).To fill this gap, we here sought to report the latest information available on non-fentanyl derived NSOs U-47700, U-50488, U-51754, U-49900, U-48800, AH-7921, and MT-45 with particular regard to their pharmacotoxicology and adverse effects on users (see Figure 1).We report a method for the detection and quantitation of 12 drugs and 2 metabolites in the same structural class as the illicit mu-opioid agonist U-47700 in human whole blood. These substances are either known or suspected to be present as potential novel opioids in illicit drug markets. The general class of these drugs was developed in pharmaceutical research programs in the 1970s, but these drugs have recently become of concern for overdoses and death in opioid users in the USA and internationally. The scope of analysis included the following compounds: methylenedioxy U-47700, ethylenedioxy U-47700, ethylenedioxy U-51754, U-69593, U-47931E (bromadoline), U-47700, U-48800, U-49900, U-51754, U-50488, propyl U-47700 and isopropyl U-47700. Additionally, two metabolites N,N-didesmethyl U-47700 and desmethyl U-47700 were also included in the scope. Drugs were extracted from human whole blood using solid-phase extraction, and the extracts were analyzed by liquid chromatography--tandem mass spectrometry. The assay was validated with respect to bias, carryover, interference, within-run and between-run precision, and accuracy. Eight medicolegal death investigation cases that had screened positive for U-48800 by liquid chromatography--time-of-flight mass spectrometry were successfully confirmed and quantified using this method. The mean and median concentrations of U-48800 in these cases were 2.5 (±2.1) and 1.8 ng/mL, respectively, with a range of concentrations of 0.27–6.2 ng/mL. Case history information including the presence of other drugs in combination are described and discussed.
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