FUB-AKB48 (also known as AFUBINACA or FUB-APINACA) is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor.
Formula: C25H26FN3O
IUPAC: N-(adamantan-1-yl)-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide.Buy FUB-AKB48 Powder online
5F-AKB48 (also known as 5F-APINACA and AKB-48F) is a synthetic cannabinoid substance of the indazolecarboxamide class. It acts as a potent agonist for the CB1 and CB2 cannabinoid receptors[1]
5F-AKB48 has been investigated in the scientific literature.[2][3][4][5] It was first identified in South Korea[6] and is available for sale as a grey area research chemical through online vendors.
Subjective effects are reported to be somewhat similar to that of cannabis with a short duration and an emphasis on intense physical sensations.
Cannabinoids are commonly smoked or vaporized to achieve a quick onset of effects and rapid offset. 5F-AKB48 is orally active when dissolved in a lipid, which can increase the duration significantly. Like other cannabinoids, it is insoluble in water but dissolves in ethanol and lipids.
Unlike cannabis, the chronic abuse of synthetic cannabinoids has been associated with multiple serious injuries deaths and more dangerous side effects and toxicity in general. Therefore, it is strongly discouraged to take this substance for extended periods of time or in excessive doses.Buy FUB-AKB48 Powder online
5F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic indazolecarboxamide as it contains a substituted indazole group. This indazole moeity is substituted at R1 with a fluoropentyl chain, a substitution shared with 5F-PB-22. Additionally, the indazole is substituted at R3 with a carboxamide group. This carboxamide group is N-substituted at its terminal amine group with an adamantane group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB48 is an analog of STS-135 in which the core indole structure is substituted with an indazole base. http://Pureresearchchemical.com/
Although this substance has not been formally studied, from analysis of the structure, it is presumed that 5F-AKB48 has a similar binding profile to that of other cannabinoids and matches many of the in vivo properties of Δ9-THC.
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