Research Chemicals
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What is Clonazolam Powder?
Clonazolam (also known as Clonitrazolam) is a novel depressant substance of the benzodiazepine chemical class which produces anxiolytic, sedative, muscle relaxant, and amnesic effects when administered. Clonazolam Powder for sale
This compound is a novel research chemical derivative of the FDA-approved drugs clonazepam (Klonopin, Rivitrol) and alprazolam (Xanax). Clonazolam is report to be roughly 2.5x as potent as alprazolam.
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Very little is known about this substance, but it has recently become easily accessible through online research chemical vendors where it is being purchase as a designer drug. Due to its extremely high potency, it is often on blotter paper or in volumetrically dosed solutions. Ingestion of raw clonazolam powder is unsafe due to its microgram-range potency and the ease in which it can lead to multi-day blackouts.Clonazolam Powder for sale
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Clonazolam has sufficient cross-reactivity to trigger a positive result on urine screening using common commercial benzodiazepine immunoassays. However, these immunoassays cannot distinguish between prescribed benzodiazepines and clonazolam (Pettersson Bergstrand et al., 2017).
Clonazolam has been detect in blood samples using liquid chromatography with tandem mass spectrometry (LC-MS-MS) (Høiseth et al., 2016; Mei et al., 2019) and in urine and serum using liquid chromatography–high-resolution mass spectrometry (LC-HRMS) (Pettersson Bergstrand et al., 2018; van Wijk et al., 2019; Židková et al., 2019).
The metabolite 7-aminoclonazolam is in urine using nano-liquid chromatography-high-resolution mass spectrometry (nanoLC-HRMS/MS) (Meyer et al.,
2016). Clonazolam is typically in low concentrations as the parent compound in urine (e.g. 7–23 ng/mL) (Pettersson Bergstrand et al., 2016). For this reason, screening for the metabolite is recommend (Meyer et al., 2016; Mc Namara et al., 2019). A lower cutoff of 10 ng/mL has been recommended for clonazolam (Pettersson Bergstrand et al.,2018).Clonazolam Powder for salehttps://www.pureresearchchemical.com/product/clonazolam-powder-for-sale/
A case report described testing of a drug sample (unconsumed tablets). Clonazolam is identify in the tablets using ultra-high-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UHPLC-QTof) (Pope et al., 2018). Neither clonazolam or its metabolites were identifiable in the patient’s urine. However, it is unclear if this was due to limitations of the testing procedure, or because the contents of the unconsumed tablet were different to the consumed tablet.
