SGT-78 Powder for sale

What is SGT-78 Powder?

SGT-78 online (also known as CUMYL-CYBINACA or CUMYL-4CN-BINACA) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug. While the in vitro activity of this compound is not disclosed in the associated patent, anecdotal reports suggest it is a potent cannabinoid agonist with an active dose of around 0.1mg.SGT-78 Powder for sale

SGT-78 for sale online and all other synthetic cannabinoids sold on this website are intended for research and forensic applications. The research chemical called SGT-78 is a designer drug with pronounced physiological and psychoactive effects and has the molecular formula C22H24N4O. The formula weight has the value 360.5 g/mol.

The toxicological and physiological properties of SGT-78 are not known. Synthetic cannabinoids like SGT-78 might display high affinity for peripheral CB1 and CB2 cannabinoid receptors.

1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-indazole-3-carboxamide and all other designer drugs sold on this website are intended for research and forensic applications.

CUMYL-4CN-BINACA (also known as CUMYL-CYBINACA or SGT-78) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug.[1][2][3][4][5][6] It is a potent agonist for cannabinoid receptors CB1 and CB2, with in vitro EC50 values of 0.58 nM and 6.12 nM, respectively.

CUMYL-4CN-BINACA is metabolized to produce cyanide, raising concerns about liver toxicity.[6] There is one reported case of hyperthermia, rhabdomyolysis, and kidney failure associated with its use.[9]

Medical uses include the treatment of nausea due to chemotherapy, spasticity, and possibly neuropathic pain.[7] Common side effects include dizziness, sedation, confusion, dissociation, and “feeling high”.[7]

Before the 1980s, cannabinoids were speculated to produce their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate.[8] These receptors are common in animals. Two known cannabinoid receptors are termed CB1 and CB2,[9] with mounting evidence of more.[10] The human brain has more cannabinoid receptors than any other G protein-coupled receptor (GPCR) type.SGT-78 Powder for salehttps://www.pureresearchchemical.com/product/sgt-78-powder-for-sale