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What is Pyrazolam?

Pyrazolam is a drug of the benzodiazepine class. Benzodiazepine drugs contain a benzene ring fused to a diazepine ring, which is a seven membered ring with the two nitrogen constituents located at R₁ and R₄. Bromine is bound to this bicyclic structure at R₇. Additionally, at R₆ the bicylic core is substitued with a 2-pyridine ring. Pyrazolam also contains a 1-methylated triazole ring fused to and incorporating R₁ and R₂ of its diazepine ring. Buy Pyrazolam Powder

How Long Does Pyrazolam Last in the Body?

Pyrazolam belongs to a class of benzodiazepines containing this fused triazole ring, called triazolobenzodiazepines, distinguished by the suffix “-zolam”.

Other Names; Pirazolam, SH-I-04

What is Pyrazolam?

Pyrazolam has structural similarities to alprazolam and bromazepam. Unlike other benzodiazepines, pirazolam does not appear to undergo metabolism, instead being excreted unchanged in the urine. It is most selective for the α₂ and α₃ subtypes of the GABA_A receptor. Buy Pyrazolam Powder

Effects of Pirazolam Powder

Pyrazolam is most selective for the α2 and α3 receptor subtypes. It is excreted by the body unchanged thus not interacting with liver enzymes like other benzodiazepines, meaning that its use in people with reduced liver function may be safer.

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Pyrazolam was originally developed by a team led by Leo Sternbach at Hoffman-La Roche in the 1970s and subsequently “rediscovered” and sold as a research chemical starting in 2012. The first official report of the drug came out of Finland in 2011 and another came from the UK in 2012.

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Pyrazolam as a Benzodiazepines produce a variety of effects by binding to the benzodiazepine receptor site and magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid (GABA) by acting on its receptors. As this site is the most prolific inhibitory receptor set within the brain, its modulation results in the sedating (or calming effects) of pirazolam on the nervous system. Buy Pyrazolam Powder