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What is 2-FDCK Crystal?
2-FDCK or 2-Fluorodeschloroketamine (AKA 2-Fluroketamine, Fluoroketamine, 2-FDK and 2-FK). Is a synthetic dissociative substance of the arylcyclohexylamine chemical class.2-FDCK Crystal for sale
2-Fluorodeschloroketamine may function in the same way as Ketamine, however scientists have been showing results ending with 2-Fluorodeschlorohydroxynorketamine (2-Fluoro-2′-Oxo-3′-HO-PCA) instead of Hydroxynorketamine (2-Chloro-2′-Oxo-3′-HO-PCA). You could expect it to have similar results, observing dissociative, anaesthetic, and hallucinogenic properties, though there is much that is still unknown about the potential of this chemical.2-FDCK Crystal for salehttps://www.pureresearchchemical.com/product/2-fdck-crystal-for-sale/
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The full chemical name of 2-FDCK is 2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one.2-FDCK belongs to a class of compounds called arylcyclohexylamines which contains various other drugs such as PCP and ketamine. Their general structure consists of a cyclohexylamine unit with an aryl group attached to the same carbon as the amine. 2-FDCK has an o-fluorophenyl group as an aryl substituent and the amine group is methylated. The cyclohexyl ring features a ketone group next to the amine position.
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The chemical structure of 2-FDCK differs from ketamine only in that there is a fluorine atom attach to the phenyl group. Ketamine has a chlorine atom in that position.
2-FDCK can be synthesize in a five-step reaction process. First 2-fluorobenzonitrile reacts with the Grignard reagent cyclopentyl magnesium bromide followed by a bromination reaction to obtain α-bromocyclopentyl-(2-fluorophenyl)-ketone. The reaction of the obtained ketone with methylamine at -40 °C then results in the formation of α-hydroxycyclopentyl-(2-fluorophenyl)-N-methylamine. Finally, the five-membered ring cyclopentanol form is expanded to a cyclohexylketone form by a thermal rearrangement reaction. HCl is use to create a water-soluble HCl salt of 2-FDCK.
2-FDCK is structurally similar to ketamine, so a similar mechanism of action is expected, but there has been no study done to confirm this. Due to the halogen in the 2 position not being a chlorine but a fluorine, the molecule is less polar. This could influence binding to proteins, such as the NMDA receptor. That ketamine primarily binds to and acts as an antagonist towards.
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